Qmetrics’ Senior Medical Scientist, Joshua M. Farber, MD, Appointed Special Advisor to the Editor-in-Chief of RadioGraphics

QNotes, Vol. 6, Issue 7

Qmetrics’ Senior Medical Scientist, Joshua M. Farber, MD, recently was invited to serve as a Special Advisor to the Editor-in-Chief, Jeffrey Klein, MD, of the RadioGraphics Editorial Board. RadioGraphics is a bimonthly journal published by the Radiological Society of North America (RSNA). The journal is devoted to continuing medical education in radiology. Dr. Farber’s term will run from March 2017 through the conclusion of the 2019 RSNA Annual Meeting.

Joshua M. Farber, MD

Joshua M. Farber, MD

In this position, for which Dr. Farber will be listed on the masthead, he will work to improve the clinical relevancy of appropriate published articles. He hopes to have clinically relevant articles include material concerning structured reporting. If the initiative is successful, elements of a structured report specific to the disease process under consideration will be published. Dr. Farber and the RadioGraphics team also hope to develop and implement a tie-in with the RSNA repository of existing structured report.

“It’s a great honor for Dr. Farber and for Qmetrics to have him serve in this capacity with RadioGraphics,” commented Edward Schreyer, CEO, Qmetrics. “It further establishes him as a respected radiologist, recognized worldwide by his colleagues. Qmetrics is grateful to have a physician of his caliber on our team.”

Dr. Farber is a board certified radiologist with nearly 20 years of clinical experience. He received his MD from the University of Pennsylvania and was a resident in radiology at New York University. He completed two formal fellowships, one in MSK radiology at New York University and one in MRI at Duke University Medical Center. Dr. Farber’s last academic position was Vice-Chair of Clinical Affairs at Indiana University, but he continues to pursue his research interests. Recently, he has published abstracts and peer-reviewed articles on articular cartilage segmentation, with a focus on clinical applications. In addition to his work with Qmetrics, he remains active in MSK and MRI society work. He has been on numerous program committees for the ISMRM, RSNA and SSR. Dr. Farber reviews manuscripts for six peer-reviewed journals, and reviews abstracts for the ISMRM and RSNA annual meetings. For more information on Dr. Farber’s publications, click here.

Two Views of an Osteophyte

QNotes, Vol. 6, Issue 6

Qmetrics recently collected some test MRI scans taken to further research and development of automated segmentation technologies.

Upon performing the segmentation and rendering the MRI into a 3D image the team noted that one of the volunteers is shown to have an osteophyte on the medial femoral condyle.

The osteophyte is circled by the yellow oval and can be seen as a ridge or protrusion that is extruding from the medial edge of the condyle.

The osteophyte is circled by the yellow oval and can be seen as a ridge or protrusion that is extruding from the medial edge of the condyle.

MRI Image of an Osteophyte on the Medial Condyle

MRI Image of an Osteophyte on the Medial Condyle

In looking at the MRI image and the 3D rendered image, the osteophyte is circled in both. Osteophytes are bony lumps that grow on the bones and are common in older patients. They are part of the diagnostic criteria that a joint is affected by osteoarthritis, though may be in the early stages of the disease.

Having the MRI and 3D rendering side-by-side provides an excellent example of how Qmetrics 3D imaging capabilities can enhance communication with patients. Although commonly viewed in profile with a traditional MRI or X-ray, viewing them in 3D has only recently become practical in clinical settings. The bone spurs are much easier for a layperson to identify in the 3D rendering. This would indicate that for persons with no imaging background, a 3D rendering may be a better tool for physicians to use when explaining the diagnoses and treatment options for patients.

To learn more about the 3D imaging options Qmetrics offers to clinical practices, researchers and orthopedic manufacturers, please contact us.

Study on the Different Effects of Running vs. Cycling in Knee Cartilage Conducted by McMaster University with Support from Qmetrics Technologies Highlighted in Canada’s Globe and Mail

QNotes, Vol. 6, Issue 5

Running vs. CyclingA study published in the January issue of the Journal of Biomechanics that features research led by Dr. Monica Maly (University of Waterloo and McMaster University) and her graduate student Anthony Gatti (McMaster University) and co-authored by Qmetrics’ Chief Medical Officer, Saara M. Tottterman, MD, PhD and Chief Technology Office, Jose Tamez-Pena, PhD, was recently highlighted in the Canadian daily newspaper, The Globe and Mail.

The study, “Acute changes in knee cartilage transverse relaxation time after running and bicycling,” compared the acute effect of running and bicycling on knee cartilage composition and morphology. It analyzed 15 young men who participated in the study, each of whom completed a 15-minute run and a 46-minute bike ride, 17-days apart. Before and after each exercise, each subject underwent an MRI scan at a research site, and the MRI data was sent to Qmetrics. Upon receipt of the blinded MRI data, Qmetrics performed a quantitative analysis using their proprietary software.

Findings from the study that were discussed in The Globe and Mail article include:

  • Although the total load on the knee joint was the same in both activities, the pattern was different. Bicycling applies a relatively low but constant load, while running applies short spikes of impact followed by no load.
  • T2 data revealed that running had deformed the cartilage enough to redistribute free water within the joint, while bicycling triggered no significant change.
  • Subject with a greater history of previous physical activity showed smaller deformations in their cartilage after both activities.
  • Cartilage appears capable of adapting and getting stronger in response to regular use.

“Qmetrics is thrilled that the study led by Anthony Gatti at McMaster is being recognized in the Journal of Biomechanics and the Globe and Mail,” said Edward Schreyer, CEO, Qmetrics. “Drs. Totterman and Tamez-Pena were pleased to scientifically collaborate with the researchers at McMaster. Our precise analysis of their MRI data enabled them to better understand how activity affects osteoarthritic patients, enabling them to make better recommendations for patient care.”

Qmetrics’ 3D analysis and quantitative measurement are available through contracts with the company or software licensing. For more information, contact us.

Qmetrics CEO to Attend ORS 2017 Annual Meeting and Present Poster Assessing Unsupervised Multi-Atlas Segmentation Errors in Context of Intended Application

QNotes, Vol. 6, Issue 4

Qmetrics’ CEO Edward Schreyer is preparing to head to the ORS 2017 Annual Meeting in San Diego from March 19 – 23.

Edward H. Schreyer, CEO

Edward H. Schreyer, CEO

Schreyer will be there to discuss a poster, “Assessment of Unsupervised Multi-Atlas Segmentation Errors in Context of Intended Application: Data from the Osteoarthritis Initiative,” authored by Edward Schreyer, Saara M.S. Totterman, MD, PhD, Joshua M. Farber, MD, and Patricia González, all of Qmetrics Technologies in Rochester, NY; and José Tamez-Peña, PhD, of Qmetrics Technologies and Escuela de Medicina, Tecnologico de Monterrey, Mexico.

The experiment outlined in the poster compares the results of a multi-atlas based unsupervised knee MRI segmentation method to the expertly-corrected segmentation in the context of their intended use. This experiment showed that measurements from the unsupervised results were statistically comparable to those resulting from the expertly corrected segmentations, further validating the performance of Qmetrics’ automated segmentation technology.

Schreyer will be presenting the poster, #932, during Poster Session 1, on Monday, March 20 from 1:15 – 1:45 PM in the Sails Pavilion of the San Diego Convention Center.

“I’m honored to return to ORS,” states Edward Schreyer, CEO, Qmetrics Technologies. “Qmetrics is proud to again share a poster and the research behind it, and I am looking forward to meeting with esteemed ORS members also at the show.”

Anyone attending ORS who would like to meet with Schreyer to discuss challenges they are facing in anatomy and cartilage segmentation research and potential solutions Qmetrics can provide, should email info@qmetricstech.com before or during the show to arrange a time to meet.

Qmetrics Technologies Announces Continued Agreement with a Top 5 Medical Manufacturer

QNotes, Vol. 6, Issue 2

Qmetrics Technologies is Pleased to Announce Continued Agreement with a Top 5 Leader in Musculoskeletal Healthcare to be a Medical Imaging Provider for Multiple Projects

Pittsford, NY – Qmetrics Technologies is pleased to announce it has signed multi-year agreements with a Top 5 medical device company to provide its advanced medical imaging technology in support of the company’s product development. Through this partnership, Qmetrics will provide support services for image processing, as well as develop custom software to assist with specific orthopedic products.

“Qmetrics is extremely pleased to continue our successful relationship with this leading manufacturer,” commented Edward Schreyer, CEO, Qmetrics Technologies. “We’ve collaborated on projects in the in the past to apply our unique medical imaging software in support of their strategic goals for orthopedic product development. Our automated segmentation technology makes their work and analysis more cost-efficient.”

About Qmetrics Technologies

Qmetrics Technologies is a specialized imaging service organization that delivers high quality medical image-based services and products to the healthcare, pharmaceutical, biotechnology and medical device industries, and clinical practices. Its accurate image segmentation, 3D modeling and quantitative analysis provide a powerful combination of scientific and medical expertise, allowing clients to more efficiently determine therapeutic efficacy with precise, reliable and measurable results. Qmetrics offers full-service imaging CRO services with a regulatory compliant core lab and quality system. Co-founded by Dr. Saara Totterman and Dr. José Tamez-Peña, Qmetrics is a privately held company based in Pittsford, NY, which provides services internationally. Visit www.qmetricstech.com for more information.

Qmetrics Technologies Announces 3D Segmentation Services

QNotes, Vol. 6, Issue 1

Product Available for Physicians, Researchers, Educators and Others Interested in 3D Renderings of Anatomy

Face Model from CT Scan

Face Model from CT Scan

Qmetrics Technologies is pleased to announce a new 3D Segmentation & Modeling service available to physicians, academic and industry researchers, educators and others interested in 3D segmentations of anatomy. The 3D segmentation and resulting models may be be useful to physicians in visualizing injury or disease and patient communication; build accurate finite models for tissue engineering, prosthesis design, etc.; for students to visualize or print clinical cases for presentation or publication; and even for the general public interested in learning more about anatomy.

“We are excited to offer 3D Segmentation & Modeling services for a wide variety of audiences,” commented Edward Schreyer, CEO, Qmetrics. “This service takes the expertise of Qmetrics Technologies and allows many users to receive a quality 3D Segmentation or Model that they can use for medical planning, gaining a better understanding of specific anatomy being studied, or having accurate models for research purposes.”

Qmetrics will accept standard anatomical images from CT, MRI, PET in a DICOM format, and return a 3D Segmented STL file ready for printing to the buyer.  The buyer has the freedom to choose a local 3D printer, print in house, or Qmetrics can identify a printer and provide their quote, details and if desired arrange for the printing. Each 3D Segmentation or Model requested will be quoted individually based upon the desired product, the anticipated time required and any unique requests. (Most quotes are anticipated to be $250 or lower, but will vary per inquiry.)

For more information about the 3D Segmentation Service and how to submit a scan, contact Qmetrics at 3Dqmetrics@qmetricstech.com.

Examples of the some models can be viewed at the 3D Segmentation page, or at Facebook/3D-Medical-Modeling.

Qmetrics Technologies’ Leaders Head to RSNA to Showcase FDA Approved Kuvia3D®

QNotes, Vol. 5, Issue 7

Recently Approved Medical Imaging Software Provides Detailed 3D Views of Patient Knee Anatomy & Soft Tissue
A cartilage defect rendering from Kuvia3D®.

A cartilage defect rendering from Kuvia3D®.

Qmetrics Technologies is pleased to announce its CEO, Edward Schreyer, and Senior Medical Scientist, Joshua M. Farber, MD, are preparing to head to RSNA 2016, the world’s premier scientific and educational forum in radiology. While at RSNA, the Qmetrics team will be showcase Kuvia3D®, Qmetrics’ FDA approved software that is used to post-process routine clinical MRI scans to provide three-dimensional renderings of anatomy. It can automatically segment fat suppressed knee MRI’s and generate 3D color maps of cartilage thickness. In addition, the platform can make linear measurements from and landmark regions of interest on the 3D renderings.

“Since gaining FDA 510(k) clearance in June, Qmetrics has been excited to introduce Kuvia3D to the medical and scientific community,” commented Edward Schreyer, CEO, Qmetrics. “We know RSNA provides an excellent venue because of the caliber of attendees.” To arrange a meeting with Qmetrics representatives, email info@qmetricstech.com prior to or during the show.

In addition to providing 3D renderings, Kuvia3D can automatically segment fat suppressed knee MRIs and generate color maps of cartilage thickness and add specific linear measurements or landmarks. Kuvia3D is available for use in clinical orthopedic settings, including private practices and hospitals and medical centers. With the supervision of a radiologist, the 3D renderings of anatomy by Kuvia3D can be used by orthopedic surgeons in pre-surgical planning and during patient consultations. Kuvia3D works with 2D and 3D fat-suppressed sequences from Philips, Siemens and GE scanners.

Qmetrics CEO to Attend ORS 2016 Annual Meeting and Present Poster Indicating Benefits of Automated Segmentation for Knee MRI Scans

QNotes, Vol. 5, Issue 3

Qmetrics’ CEO Edward Schreyer is preparing to head to the ORS 2016 Annual Meeting at Disney’s Coronado Springs Resort later this week.

Schreyer will be there to discuss a poster, “Performance Assessment of an Automated Segmentation System for Knee MRI Scans,” authored by Patricia González, Joshua M. Farber, MD, Saara M.S. Totterman, MD, PhD, and Edward Schreyer, all of Qmetrics Technologies in Pittsford, NY; Antonio Martínez-Torteya, PhD, of ITESM in Monterrey, Mexico; José Tamez-Peña, PhD, of both ITESM and Qmetrics; and Bryan J. Morrison of Zimmer-Biomet, Warsaw, IN.

Comparison of Expert Radiologist Segmentation vs. Unsupervised Automated Segmentation of Knee Anatomy

Comparison of Expert Radiologist Segmentation vs. Unsupervised Automated Segmentation of Knee Anatomy

The results discussed in this poster showed that using the fully-automated system, the bone and cartilage segmentations of the femur, patella and tibia from knee MRI scans were not significantly different from manual segmentations performed by an expert musculoskeletal radiologist.

Schreyer will be presenting the poster, #1307, during Poster Session 2, on Monday, March 7 from 6:15 – 7:00 PM in the Veracruz Exhibit Hall of the Disney’s Coronado Springs Resort.

“We’re excited to attend ORS,” states Edward Schreyer, CEO, Qmetrics Technologies. “Not only are we proud to share the poster and the findings from the research behind it, but we look forward to meeting with the esteemed members attending the show.”

Anyone attending ORS who would like to meet with Schreyer to discuss challenges they are facing in knee anatomy and cartilage segmentation research and potential solutions Qmetrics can provide, should email info@qmetricstech.com before or during the show to arrange a time to meet.

Qmetrics Team Members to Attend RSNA

QNotes, Vol. 4, Issue 7

Edward H. Schreyer, CEO

Edward H. Schreyer, CEO

Qmetrics CEO, Edward Schreyer, and Senior Medical Scientist, Joshua M. Farber, MD, are preparing to head to RSNA 2015, theworld’s premier scientific and educational forum in radiology. This six-day meeting in Chicago, IL, includes educational programs for radiologists, radiation oncologists, physicists in medicine, radiologic technologists and allied health care professionals. The Qmetrics team anticipates the yearly meeting for its valuable educational opportunities and as a constructive environment in which to collaborate with colleagues.

Joshua M. Farber, MD

Joshua M. Farber, MD

This year, Dr. Farber will sit on the RadioGraphics MSK panel to judge posters and select ones for publication. RadioGraphics is a bimonthly journal devoted to continuing medical education in radiology.

Schreyer anticipates the event, saying, “We have several meetings with collaborators already scheduled and look forward to catching up with many others as well. This meeting brings the best of the best in radiology together, and Qmetrics is proud to be in such esteemed company. We have some new offerings to discuss while we’re in Chicago, and hope for a productive trip.” Anyone attending RSNA who would like to catch up with Qmetrics should email info@qmetricstech.com before or during the show.